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Why are selective serotonin reuptake inhibitors (SSRIs) so popular?

D

Duckbruck

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Is it simply easier/safer to prescribe an SSRI than any other type of treatment?
Are most cases of depression caused by a serotonin problem?

When SSRIs came out on the market at the beginning of the 90s, big pharma marketed them as the new wonder pills with almost no side effects, but today we know that they cause substantial sexual side effects, gastrointestinal side effects, dizziness, sleep disturbances (insomnia, sleepiness), headaches, agitation & tremor / shaking...

I don't want to even start on zombification, lack of emotions, apathy and so on...

And what about Citalopram/Escitalopram-induced QTc prolongation? Wasn't that always an anti-TCA argument? "Bad TCAs may cause problems with your heart, but SSRIs don't!"

And for all we know right now, SSRIs don't show greater efficacy than TCAs, TeCAs, MAOIs, Atypicals etc.

I will not deny that there are people out there, who benefit from SSRIs, but that's also true for TCAs, TeCAs, MAOIs, Atypicals...

So what's the big deal with SSRIs?
Why are they randomly prescribed like children's candy?
 
blacksmoke

blacksmoke

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even worse still is the 5 htp medication darn well nearly finished me off but hey ho the doc is saying it was anxiety that caused a serious and sudden side affect. happen twice with several months apart. :evil:
 
D

Duckbruck

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even worse still is the 5 htp medication darn well nearly finished me off but hey ho the doc is saying it was anxiety that caused a serious and sudden side affect. happen twice with several months apart. :evil:
(y)
What else did you try? :)

Most doctors don't take the condition of the patient into account.
For example, if there is a depressive patient, underweight, with insomnia, agitation and with gastrointestinal problems, then prescribing him an SSRI like Sertraline or something like Bupropion (Wellbutrin) will probably make him feel worse. Better would be Mirtazapine, Maprotiline or an classical TCA. Or even a combo, for example Sertraline + Mirtazapine. But no, let's play the SSRI carousel...
 
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cpuusage

cpuusage

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Why are selective serotonin reuptake inhibitors (SSRIs) so popular?

The Global Pharmaceutical Industry is worth 100 Billion pounds profit a year, that's why.

It doesn't matter what the truth is of mental / general health & psychiatric / all pharmaceutical drugs in that context.

It doesn't matter what any health / social implications are.

It's the same as the War of / on Terror - it doesn't matter how many millions of deaths; it's worth Trillions.

It's the same as any other area; the environmental destruction, Global Warming, Social Inequality etc - Sum Equals = $$$$$$$$$$ = God.
 
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cpuusage

cpuusage

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It's the same as any other area; the environmental destruction, Global Warming, Social Inequality etc - Sum Equals = $$$$$$$$$$ = God.
People spoke the truth about all this 70 years ago & still are - the majority aren't interested, so it doesn't matter - as long as the dissent / critics can be kept to the minority it's a winning game, it's all about numbers.

America’s Most Admired Lawbreaker - The Huffington Post
 
blacksmoke

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(y)
What else did you try? :)

Most doctors don't take the condition of the patient into account.
For example, if there is a depressive patient, underweight, with insomnia, agitation and with gastrointestinal problems, then prescribing him an SSRI like Sertraline or something like Bupropion (Wellbutrin) will probably make him feel worse. Better would be Mirtazapine, Maprotiline or an classical TCA. Or even a combo, for example Sertraline + Mirtazapine. But no, let's play the SSRI carousel...
it was mirtazapine which is a 5htp and that was pure horse shit. i immediately felt very out of sorts and thought thank goodness i am at mine and not outside or in the car forward wind and i take the natural version of 5 htp taking it for oh about 2 weeks and i had a major and sudden side affect whilst in the car. plus i was also taking B100 and omega 3 and on antihistamines for horsefly bites.

later on i researched the 5htp and basically it seems like i had a serotonin rush which apparently is quite dangerous. i also researched the other stuff i was on and discovered that the combo i was on was dodgy. so all in all i have learnt that what with the 5htp i am obviously very sensitive to it been on the ssri before and that so called natural medicine is just as dangerous if you get it wrong which is what i very nearly did. some miracle that i didnt cause a major problem (a far as i can tell....) to myself and because the second episode happened whilst i was in a car it could have had very serious outcome for not just me but for other people......

i also had lots of what i call other episodes for a number of weeks after. i was not allowed to drive for a month.

so it aint all paradise in medication land. i wonder if other peeps have had this reaction to mirtzpan.
 
The Duellist

The Duellist

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In my country, the GP, Big pharma, and local pharmacy share the same bed. It’s about profit margins not about helping people. This is the ugly cycle:

Big pharma sales rep visits your GP and offers them free(not for sale) samples of the medicines they need to push.

Then Big Pharma rep visits your local pharmacy and gifts them free(not for sale) samples of the medicines they need to push.

The GP has no use for the free meds, since he can only legally prescribe but not sell the meds.

GP visits local pharmacy and gifts them the samples they received from Big Pharma.

The GP does this so that the local pharmacist will continually refer patients to him or her. The doctor is now making more money.

The pharmacy now has inventory, they will sell to you for which they never paid a dime.. Their profit margin is now 100%..Nor too shabby , huh?

Now Big Pharma has the GP in their pocket. Your GP will not dare prescribe anything other than what big pharma wants, because if they don’t, there’s always someone willing to do it and the moneymaking relationship will be terminated. Not to mention the sale of free samples is illegal in my country.

My friend from the past was a pharmacist. One day he invited me to his apartment to have a few drinks. When he was sufficiently drunk, he decided to unlock a closet door which had a conbination lock on it. .. No there was no body in the closet, instead the entire closet was jam packed with samples that would be repackaged and converted to “for sale” items. The approximate value of the meds was 1 million which will be sold at near 100% profit margin at his local store. The reason he held the inventory in his closet was to elude government inspector, who do surprise spot checks on inventory .. He thought he was fucking Pablo Escobar

Finally, the inventory will be sold very slowly and to cash paying customers so the increasse in revenue won’t be detected and no taxes will be paid on the revenue stream. The entre system is corrupt.

Never trust this unholy trinity.:)
 
Kerome

Kerome

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These drugs are also often prescribed to the elderly as a way of sedating them. It's a pretty gruesome business. There is no real need for them to be taking this medication but once they are on them no one seems to dare take them off.
 
blacksmoke

blacksmoke

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gosh Duel and here was me thinking i was fairly cynical and untrusting of the medical world and it turns out it stinks far more than i imagined no open window or candle will get rid of that putrid smell of deceit

at times i feel like being radical and maybe in a parallel universe i might just say to the doc-----
 
blacksmoke

blacksmoke

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These drugs are also often prescribed to the elderly as a way of sedating them. It's a pretty gruesome business. There is no real need for them to be taking this medication but once they are on them no one seems to dare take them off.

yes i witnessed this with my dad.i was shocked by the shite they pumped into him. that was far more distressing than all the other stuff. -------
 
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