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Wellbutrin SR switch to XL



Oct 19, 2018
My psychiatrist had me taking Wellbutrin SR 300mg once a day, even though I read it's most commonly twice a day. I'm now switching to 300mg XL once a day.

Wondering is anyone has made that switch? Also wondering if it will be a strange switch because Sr at 300 would give me more in my system at once than xl 300, right? I assume it will level out after a few days? Hopefully?


Well-known member
Nov 3, 2018
New Jersey
yes it will smooth out. Extended release is something i have taken for years and has worked out for me. you may go thru a short period of adjustment but since you aren't switching meds, it shouldn't be a big deal.