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Switching to Venlafaxine

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WeirL1987

New member
Joined
Jun 15, 2019
Messages
2
Location
Scotland
Hi, I have been on and off sertraline for a good few years max dose 200mg for anxiety and depression. It seems it’s no longer working. I have been weaning off it for the last few weeks and will have a washout period of a few days and start Venlafaxine on Wednesday. The doctor has prescribed 75mg once a day. I have read the patient Information Leaflet and it says they are the immediate release ones and should be taken twice a day. Is this normal to be prescribed immediate release once a day? Surely it will run out mid way through the day. Sorry for waffling.
 
megirl

megirl

Well-known member
Joined
Apr 9, 2010
Messages
7,260
Location
NZ
I am also on venlafaxine despite being immediate release it will take time for it to be broken down
It depends on a medications 'half life' it may have a half life of 12 hours which means it will peak at 12 hours then the potency will drop off but as its taken every 24 hours the drug in your body will even put once you start taking it daily
 
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WeirL1987

New member
Joined
Jun 15, 2019
Messages
2
Location
Scotland
Thank you, I wasn’t sure if that was right but thank you for clarifying that. Really wouldn’t want to start going nuts in the afternoon lol. The last few weeks coming off the sertraline has been bad enough. Just really want to star feeling better again. Sertraline used to always do the trick. Thanks again for your reply.
 
megirl

megirl

Well-known member
Joined
Apr 9, 2010
Messages
7,260
Location
NZ
Exactly immediate release can be confusing. There are many drugs that are immediate release but it depends on their half life.
 
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