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Recovery, not progressive deterioration, should be the expectation in schizophrenia

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firemonkee57

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Mar 23, 2009
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Recovery, not progressive deterioration, should be the expectation in schizophrenia

Since the time of Kraepelin, schizophrenia has been considered to be a progressive deteriorating illness [1]. This perspective has been bolstered by a generation of studies demonstrating deficits in brain volumes on magnetic resonance imaging (MRI) scans and in performance on a broad range of cognitive tasks in individuals with schizophrenia [2].

Despite the introduction of effective pharmacological treatments and evidence-based psychosocial interventions, fewer than one in seven people affected are considered to meet criteria for recovery [3]. The possibility that the pathophysiology of schizophrenia involves mechanisms that progress over the longitudinal course of the illness is often assumed to explain the poor outcomes observed [2]. Advocates for early intervention have embraced this paradigm as it implies that early treatment has the potential to arrest a disease process that would otherwise continue on an unrelenting march to severe mental deterioration.

While progression of an active disease process would provide a compelling explanation for the poor outcomes so commonly observed, it is not consistent with what we have learned from modern studies of the longitudinal course of structural brain abnormalities, cognitive deficits and clinical outcomes associated with schizophrenia [4]. Rather, schizophrenia appears to be associated with stability of these measures over the longer term. It is time to consider the possibility that clinical stability and recovery rather than progressive deterioration should be the expected outcomes from schizophrenia.

Recovery, not progressive deterioration, should be the expectation in schizophrenia - Zipursky - 2015 - World Psychiatry - Wiley Online Library
 
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wannabegooroo

Guest
it can improve, depending on your definition of "recovery", it's possible to deactivate the positive and negative symptoms even after years of illness, it's more about adapting yourself mentally and accepting your limitations. If you get stressed your body will use the same pathway to protect itself
 
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