Shaun3210 - despite everything I have to agree with you about the future, yes, even I am able to conceive that it is possible than one day there may be an opening for a particular sort of therapy for me, but not now, not now.
Unlucky, you've written, "MAybe it is just me and I'm just not open to getting better." I wouldn't, myself, take that point of view unless the MH professional treating me had 1) found out everything about me including life history and thought world, 2) that they had incorporated into their approach with me a full understanding of me as an individual so that their suggestions were likely to chime with me as an individual, 3) had fully acknowledged and taken into account the impact of life problems, 4) had exhausted all possible treatments.
I need to correct something in my reference to research at the Institute of Psychiatry. It is 20% of the population who are resistant to all anti-depressants not 30%.
“Making sure the right anti-depressants are prescribed 1
If you go to your doctor with depression, they will almost guess which anti-depressant to prescribe. But some people don’t respond to certain types of drugs and may not get better until their GP switches them to another sort.
A new international research project aims to banish guesswork and the ‘try it and see’ approach by developing a test to help doctors decide which anti-depressant will best suit patients’ genetic make-up.
The IoP is leading a team of scientists and clinicians from 10 countries who will study 1000 depressed people over three years and aim to link their genetic profile with their response to different types of medication.
These people will be treated with one of the two types of drugs currently on the market. One affects serotonin in the brain, the other affects noradrenaline, another chemical that send messages between brain cells.
By monitoring patients’ responses and analysing their genetic make-up, the researchers hope to find a way to help doctors know which anti-depressant will suit each patient best, depending on the design of their genes.
The GENDEP Project, which was awarded 7.5 million euros by the European Commission back in March 2004, has ‘the potential to revolutionise the treatment of depression’, says Professor McGuffin 2
There is, however, about 20 per cent of the population, who don’t respond to any drugs at all. ‘At the moment, we don’t know why that is,’ he says."
1 Research at the Institute of Psychiatry 2005-2006
http://admin.iop.kcl.ac.uk/randd/downloads/IoP_Research_Report_2005-6.pdf
2 Peter McGuffin, Professor of Psychiatric Genetics at the Institute of Psychiatry