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Other not so common anti depressants...?

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dewey

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I've recently heard about Pregabalin and Duloxetine. Who has experience of these?

Want to learn more on people's different experiences with anti depressants. Obviously what works for one person won't work for another, but still curious.

So I'd say the most commonly anti depressants used are prozac, sertraline, escitalopram, I'm probably forgetting a couple. Also quetiapine/Seroquel though technically apparently that is an anti psychotic.
 
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iWILLOBTAINMENTALHEALTH2

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Zoloft is the only anti depressant that has ever helped me. I've tried almost all of them out there too.
 
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dewey

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Zoloft is the only anti depressant that has ever helped me. I've tried almost all of them out there too.
Was it steady going for you on the Sertraline/Zoloft? When you started out did you get any bad symptoms?
When I had sertraline the depression I had was excruciatingly bad. Just horrendous. So I stopped it.
You also tried Pregabalin or Duloxetine at some point?
 
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schizolanza

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Venlafaxine has helped me. Missing a dose or withdrawal is hell and just not an option.
 
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dewey

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Venlafaxine has helped me. Missing a dose or withdrawal is hell and just not an option.
It's improved stuff for me but that's not saying much as I was abysmally low before. I wanna get off it and onto something better. My symptoms are still too bad and I've tried varying dose.


Obviously never completely withdraw, without a doctor gradually lowering and monitoring you. That is mental torment.
 
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schizolanza

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I'm confused. Are you currently taking venlafaxine? Effexor?
 
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schizolanza

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Oh ok. Well good luck with a very long and nasty withdrawal. I hope your one of the lucky ones who don't have to suffer too much!
 
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dewey

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Oh ok. Well good luck with a very long and nasty withdrawal. I hope your one of the lucky ones who don't have to suffer too much!
It should be fine. I'm doing it slowly. I can't really suffer any worse symptoms than I've already had pretty much the whole of my life. So I'm prepared :) Thank you.
Has venlafaxine completely cleared up your depression? What symptoms do you still get? Do you feel any numbness? Curious...... I still get a lot of symptoms, but I'm better than I was before I started taking them. It hasn't cured my depression but it's stopped me breaking out in tears so much etc
 
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iWILLOBTAINMENTALHEALTH2

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Was it steady going for you on the Sertraline/Zoloft? When you started out did you get any bad symptoms?
When I had sertraline the depression I had was excruciatingly bad. Just horrendous. So I stopped it.
You also tried Pregabalin or Duloxetine at some point?
No I don't and never have taken either of those. Zoloft killed my sex drive and pleasure. It made me gain weight too. But I'm glad it took away the suicidal feelings I was having. Good luck. I hope you get on the right anti depressant.
 
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schizolanza

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It should be fine. I'm doing it slowly. I can't really suffer any worse symptoms than I've already had pretty much the whole of my life. So I'm prepared :) Thank you.
Has venlafaxine completely cleared up your depression? What symptoms do you still get? Do you feel any numbness? Curious...... I still get a lot of symptoms, but I'm better than I was before I started taking them. It hasn't cured my depression but it's stopped me breaking out in tears so much etc
Venlafaxine lifted me out of a suicidal depression in 2006 after a complete melt down hospitalization. I tried loads of antidepressants but nothing helped until I tried venlafaxine.
 
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JCPraha

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I am currently taking Brintellix (Trentillix is U.S.) it is a newer anti-depressant and works on different pathway than older SSRIs. It has an effect on different sub-types of serotonin receptors. It has helped me, to some extent, but my depression is definitely treatment resistant.
 
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Jules5

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Jan 27, 2019
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I am on Venlafexine for 9 years now it has helped and boy I would love to get off it but the withdraws will be to much I definitely have to be on something because of my moods So so far Venlafexine is it Hugs to all
 
LadyDomino

LadyDomino

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I was put on progablin to help easy anxiety - it made a difference for about 6 weeks, then the effect petered out and I was left with uncomfortable side effects, including a mouth full of ulcers which made eating hard. I took myself off it, slowly. But even so got the usual side effects of withdrawel, of unpredictable moods, headaches, depression etc.

Duloxitine is the best anti depressant I've been on. I'm currently on 90mg in the morning, and although I don't feel great, its far better in terms of side effects than any of the other anti depressants I've had.
 
daffy

daffy

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I take duloxitine 120 mg on a morning and mirtazipine 45 mg at night. I do think that the duloxitine helps calm me as I can tell when I’ve forgotten to take it as the anxiety is much worse
 
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