• Share. Be Supported. Recover.

    We are a friendly, safe community supporting each other's mental health. We are open 24 hours a day, 365 days a year.

Long term effects from antidepressants.



Active member
Jan 1, 2020
Does anyone experience having a hard time feeling regular emotions such as excitement, happiness, joy? I was on anti depressants for a long time and I feel like I am experiencing long term effects from them. I got myself off them about two years ago and now take 150mg of quetiapine to which I have been on for two years.
For the longest time all I wanted to feel was numb because I couldn't handle my emotions.. now I have none besides feeling depressed, anxiety or on edge most of the time. I would love to be able to feel excited again.


Well-known member
Jan 7, 2020

I was in a similar condition. I was on Lexapro for 16 or more years. I quit it .....severe withdrawal then the relapse of severe depression followed (current).

Like you, while I was on Lexapro, I was numb. I was not depressed but I was not normally? happy. It’s hard to explain. Others told me i’m always calm. But it’s not true. I was unable to feel joy or excitement.
Similar threads
Thread starter Title Forum Replies Date
U Long term Multiple Sclerosis, waiting for diagnosis. Depression Forum 2
Desire less Why it's so hard to get out of long-term depression!!! Depression Forum 15
J Starting long term therapy Depression Forum 18
A Self-defeating behavioral patterns in reaction to long-term depression Depression Forum 3
L Long term fluoxetine use and suicidal ideation Depression Forum 2
N Brain damaged through long term depression any comments Depression Forum 10
O People with long term depression, how do you sleep? Depression Forum 9
J Questions about long term use of Klonopin Depression Forum 1
T Please help me understand my partners behaviour who is long term depressive Depression Forum 1
I Depressed after a long term relationship has ended Depression Forum 2
O Has anyone successfully treated their depression long term without medication? Depression Forum 6
C Daughter 22 suffering long term depression Depression Forum 3
P No interest in life, long term depression... long rant Depression Forum 4
A long term depression Depression Forum 2
D Combination of long-term loneliness and existential crisis Depression Forum 5
H Long time isolated, now can't socialize Depression Forum 1
Jam1990 Doing better than I have in a long long time Depression Forum 9
M How long you was dealing with depression before search and join to a forum? Depression Forum 8
L Depressed for a long time Depression Forum 6
C Long distance Relationship and restrictions Depression Forum 1
T it’s been too long Depression Forum 1
R Apathetic and lost (sorry its long) Depression Forum 5
jajingna Long day Depression Forum 8
trueloveseeker Pretty Extreme Depression From Basically Being Alone For Too Long Depression Forum 3
S Antidepressant discontinuation after long time no response Depression Forum 8
M Long story... Depression Forum 1
N A long-overdue vent (or, an essay on uncertainty) Depression Forum 1
A A long winded thread; grab some coffee Depression Forum 2
Drawings_T Looking for inspiration, been struggling so long Depression Forum 3
K Coping with depression and long distance relationships. Depression Forum 1
B Can being single for a long time mentally drain a person? Depression Forum 24
M It's going to be a LONG one oops so sorry Depression Forum 2
A walking around veiled, how long will this last. Depression Forum 6
M Long Distance Relationship + Depression Depression Forum 2
LonelyTengu How long do I have to keep waiting? Depression Forum 5
Lone_wanderer I've been down so long it seems like up to me. Depression Forum 9
antonialost Long post...would appreciate if somone reads, offers insight? Depression Forum 9
M Any here has not had social interaction in long time - and seeks for it ? Depression Forum 4
J Can't stop feeling guilty - Please Help - Long Post Depression Forum 6
J Thought I was getting better - Help Appreciated - Long Post Depression Forum 7
V Feeling low for a long time Depression Forum 6
Molly05 Advice please, personal and very long Depression Forum 4
9 Long distance relationship Depression Forum 2
W Worst I’ve felt in a long time Depression Forum 1
PurpleDaffodils Life Long Stress; Lack of Motivation Depression Forum 1
0 How do I help my partner? I'm so sorry this is long but I really really need some advice. Depression Forum 3
M How long do depression dips last for? Depression Forum 3
S How Long Depression Forum 11
B Don't know how long I can do this Depression Forum 5
Z (This is long) Trusting the wrong person made my depression worse Depression Forum 7

Similar threads