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Lamotrigine effects

Boomerang

Boomerang

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Jan 8, 2017
Messages
49
Over 2 years for me and mostly i have been high in energy but now i am depressed. The depression came on gradually. I never felt very stable until this depression which has seen me stably depressed. I know what every day will be like now. My Dr says it is not a good AD but i don't think it is good at preventing highs either but it is the best mood stabilizer i have ever taken and i have had most. I have retained my emotions and not been through the flat and apathetic feelings that other ones have made me feel. I have not had akithisia and have not had insomnia. I have not gained weight, if anything i have lost. Any side effects went away. It is one that people say needs to be increased and increased but my Dr did not increase but added an AD. If you have to work, i can see that it might not be good enough for some people, but an increase for me might have stopped the instability of energy. It never did last throughout the day also. I needed an afternoon kip or an afternoon quiet time. I found agitation to be a problem sometimes.
 
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RubyGloom

Guest
Over 2 years for me and mostly i have been high in energy but now i am depressed. The depression came on gradually. I never felt very stable until this depression which has seen me stably depressed. I know what every day will be like now. My Dr says it is not a good AD but i don't think it is good at preventing highs either but it is the best mood stabilizer i have ever taken and i have had most. I have retained my emotions and not been through the flat and apathetic feelings that other ones have made me feel. I have not had akithisia and have not had insomnia. I have not gained weight, if anything i have lost. Any side effects went away. It is one that people say needs to be increased and increased but my Dr did not increase but added an AD. If you have to work, i can see that it might not be good enough for some people, but an increase for me might have stopped the instability of energy. It never did last throughout the day also. I needed an afternoon kip or an afternoon quiet time. I found agitation to be a problem sometimes.
I guess I am also stable depressed. But I have the apathy. I can still feel my mood cycle, it is shorter as far as 'highs' go, but it is all internal energy now, no high feelings. Just apathy, lack of anything. The only plus side is I'm not so bothered by things as when I'm depressed, and I don't think so much. Where I mostly hate the thought of going to work, etc, when 'high' now, the difference is I'm not thinking that I'm hating it. I'm just automatically doing it without it being difficult. So very unlike being 'high' in un medded times. And only lasts a short time (up to a week) before I lose the energy.

I also get tired in the afternoon. I have to take the whole dose in the morning, I did try splitting it between morning and lunch (any later and I it stops me from sleeping), but I kept forgetting to take it at lunch. So just easier to take it in the morning.

I also feel more productive later on if I forget to take it.
 
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gypsiqueen

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Jul 26, 2016
Messages
31
I've been on Lamictal since 1999, and I've never had cognitive problems with it. I tried to go off of it a few times, but I crashed hard so the pdoc put me back on it.

I do have cognitive problems though. At times they've been really severe, to the point that I wasn't able to work. I did an all day evaluation at a psychologist's office, and what came out of it was that I had all of the knowledge inside, but I just couldn't get to it. It was in there, but I couldn't access it. Like names. I know what the name of my coworker is, but I can't bring it up. Then randomly 6 hours later it will pop into my head. And I would literally forget what I said/did 5 minutes before. It was frustrating, and my hubs was very frustrated. He tried not to be, because he knew it wasn't my fault, but he still had frustrations about it.

They didn't know if it was my illness that caused it, or the medications I was on that caused it. I didn't go off of the meds because I really wasn't stable. It's been a few years since I had the eval, and things have gotten better in a lot of ways, but I still have problems reading, and sometimes when I'm stressed, my brain shuts off and I forget what I'm saying halfway through the sentence, or I can't recall names or places. I'm still on the same meds I've been on since 2011. I have only read one book since 2010 because I just can't get through it. After a few pages my brain is like, ok, that's enough. Sometimes I have to read that same pages over because I can't remember what I read, or when I read it, it doesn't make much sense. The one book I read was a children's book, because they don't have super complex ideas and they don't have have a lot of characters that I have to keep track of. It sucks, but that's how it is. My mood is stable, and that's what counts for me.
 
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RubyGloom

Guest
I guess we shouldn't be surprised considering that it's a drug which is directly affecting our brains.
The part explaining the inhibiting of glutamate interesting re.memory issues and apathy.

Lamotrigine – HOPES
Lamotrigine belongs to a group of medications called anticonvulsants, which are used to control seizure disorders. Lamotrigine acts on the central nervous system to control the number and severity of seizures. It is thought to suppress the activity of certain parts of the brain and the abnormal firing of nerve cells that cause seizures. In psychiatry, lamotrigine may be used as a mood stabilizer. In the laboratory, researchers have found that lamotrigine also inhibits release of the neurotransmitter glutamate. This is important because glutamate may play a role in nerve cell degeneration in the brains of people with HD (Huntington's disease) so reducing the amount of glutamate released makes lamotrigine a potential treatment for HD.

From wiki
Glutamate is an amino acid, one of the twenty amino acids used to construct proteins, and as a consequence is found in high concentration in every part of the body. In the nervous system it plays a special additional role as a neurotransmitter: a chemical that nerve cells use to send signals to other cells. In fact, glutamate is by a wide margin the most abundant neurotransmitter in the vertebrate nervous system.[1] It is used by every major excitatory information-transmitting pathway in the vertebrate brain, accounting in total for well over 90% of the synaptic connections in the human brain.

Because of its role in synaptic plasticity, glutamate is involved in cognitive functions such as learning and memory in the brain.[2] The form of plasticity known as long-term potentiation takes place at glutamatergic synapses in the hippocampus, neocortex, and other parts of the brain.

Glutamate (neurotransmitter) - Wikipedia
 
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cpuusage

cpuusage

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I guess we shouldn't be surprised considering that it's a drug which is directly affecting our brains.
The part explaining the inhibiting of glutamate interesting re.memory issues and apathy.
All psychiatric drugs are damaging (to the body/brain) & sedative - Biomedical psychiatry is focused on treatments that disable the brain -

http://www.huffingtonpost.com/dr-peter-breggin/braindisabling-treatments_b_85828.html

The argument is whether such treatment pays off within a risk/benefit scenario, that the drugs are better than the underlying condition/experiences of psychological/emotional distress/difficulties?

i think it's very debatable what the true benefits are of the current biomedical paradigm in relation to mental health, as well to a degree within the whole area of general medicine.

There are, imo, viable alternatives that could be used. But this civilisation/society/culture is the ways it all is/how it is.
 
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RubyGloom

Guest
All psychiatric drugs are damaging (to the body/brain) & sedative - Biomedical psychiatry is focused on treatments that disable the brain -

Brain-Disabling Treatments in Psychiatry: Drugs, Electroshock and the Psychopharmaceutical Complex | The Huffington Post

The argument is whether such treatment pays off within a risk/benefit scenario, that the drugs are better than the underlying condition/experiences of psychological/emotional distress/difficulties?

i think it's very debatable what the true benefits are of the current biomedical paradigm in relation to mental health, as well to a degree within the whole area of general medicine.

There are, imo, viable alternatives that could be used. But this civilisation/society/culture is the ways it all is/how it is.
Yeah. It's interesting to find out in what ways the drug affects certain bits and you can recognise these in your own side effects. Not good, but interesting.
Not great that it affected my ability to manage household finances when I've done it for years. I've not noticed the missing words and names so much, so hoping it was the increase in dose that upset my brain and it's worked out how to function again. I'll find out when I next try and work out the money stuff.

I told myself when I started it that I would take it to (potentially) give myself a pharmaceutical year off. What's annoying is that regardless of how is making me feel and how it's affecting me personally, as far as family goes, I'm being more functional for them. The ups and downs are not really there, so I'm more consistent.
Unfortunately for me, just more consistently miserable.

So now I don't know what to do in the near future.
I could end up adding another med, to try and help myself, but then it's a case of getting stuck on pills, then pills to fix the other pills etc
I didn't want that, for me.

But who should I consider more importantly?
 
cpuusage

cpuusage

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But who should I consider more importantly?
It is a conundrum. i've found a trade off with a lowish dose of one medication, & doing what i can for my own life & healing, it has been & is hard.

i expect that my life would have & would be easier to just increase the neuroleptic, & add in other drugs as well, But there wouldn't be the same quality of life in ways.

i resent the ways this current society/system is, given that i think there are viable alternatives that could be used, at the least such alternatives could be used in conjunction with the present system/treatment. i think it's all largely shit & i always have done, But then what is truly advanced about this Global Civilisation/Culture anyway? The entire place is backwards.
 
R

RubyGloom

Guest
Told to whack on another 100mg
And if that doesn't work grab a bag of Escitalopram.
What the fuck have I got to lose. Might as well take em all.
Fuck this, I'm never going to feel better.
 
cpuusage

cpuusage

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It's making me feel worse and better

:cry:
Yea, it's a peculiar one once on the psychiatric drug path. Few ever get off it. 80% of Americans & 50% of the UK now on one or more permanently prescribed pharmaceutical, for either / & physical / mental health problems, & rising exponentially - along with all the other ways we're being altered through chemical, psychological, electromagnetic, digital & other means.

Brave New World Here We Are - Whoopee! Isn't it fun. :)
 
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