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Every medication seems to quit working for me

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needthecaffeine

needthecaffeine

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I have a loooong history of different SSRIs I’ve taken and every single one of them stops working for me after about a year or so. I’ve been taking Prozac and it worked very well for me. It wasn’t the best but getting out of bed didn’t feel as difficult. Now once again I’m having trouble and I have thoughts of being better off gone everyday.

anyone have any medication recommendations or similar experiences that they’ve been able to overcome? So far I’ve taken lamictal, pristiq, lexapro, Paxil, Zoloft and then the current one I’m on, Prozac. I’m losing hope
 
Marrex

Marrex

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Without knowing your exact diagnosis, I can tell you what has worked/not worked for me. I take this medication called "Abilify" or the generic version of it, anyhow. I contribute it the most to what mood stabilization I have gained, along with Sertraline. I'm pretty sure that one is for Depression. My mom took or at least takes prozac, and I think it's worked for her for a long time now. But, do keep in mind the body doesn't stop changing until around 25, and as you probably already know your brain chemistry changes along with it, I'm still a year away from that mark but so far those two have worked for me. I hope you get to finding the right medication for you!

Edit: Lamictal didn't work for me, but I don't think it caused anything negative, either. Also, Abilify has been the one I've been on since I was 15, so almost a decade now!
 
L

lifecangetbetter

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I have a loooong history of different SSRIs I’ve taken and every single one of them stops working for me after about a year or so. I’ve been taking Prozac and it worked very well for me. It wasn’t the best but getting out of bed didn’t feel as difficult. Now once again I’m having trouble and I have thoughts of being better off gone everyday.

anyone have any medication recommendations or similar experiences that they’ve been able to overcome? So far I’ve taken lamictal, pristiq, lexapro, Paxil, Zoloft and then the current one I’m on, Prozac. I’m losing hope
it may help a little if you describe what you're trying to treat? depression, ocd etc?
 
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siliconom

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They are all SSRI

You got heaps of other choices

SNRI - venlafaxine, duloxetine

TCU - older ADs what correspond to above

Vortioxitine - newest class AD

Mirtazapine - often used for folk what don't respond to above

Antipsychotics at medium dose

MAOI - oldest class of AD. Very effective but you can't drink alcohol or eat cheese
 
L

lifecangetbetter

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They are all SSRI

You got heaps of other choices

SNRI - venlafaxine, duloxetine

TCU - older ADs what correspond to above

Vortioxitine - newest class AD

Mirtazapine - often used for folk what don't respond to above

Antipsychotics at medium dose

MAOI - oldest class of AD. Very effective but you can't drink alcohol or eat cheese
yes this is correct except its TCAs not TCUs. with refractory depression they typically add an antipsychotic
 
Wishbone

Wishbone

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Have you ever read up on other conditions/disorders to see if any others match up with your symptoms? Personality disorders, as an example? Maybe therapy is what is needed rather than medication?
 
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lifecangetbetter

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Trying to treat anxiety and depression
You could ask your doctor to try an snri. It's similar to ssris in that it works on serotonin but is different by also working on norepinephrine. There's also wellbutrin which works on dopamine and gives people energy to help them get out of bed in the morning
 

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