• Hi. It’s great to see you. Welcome!

    Our forum members are people, maybe like yourself, who experience mental health difficulties or who have had them at some point in their life. Amongst our membership there is a wealth of expertise that has been developed through having to deal with mental health issues.

    We are an actively moderated forum with a team of experienced moderators. We also have a specialist safety team that works extra hard to keep the forum safe for visitors and members.

    Register now to access many more features and forums!

  • Safety Notice: This section on Psychiatric Drugs/Medications enables people to share their personal experiences of using such drugs/medications. Always seek the advice of your doctor, psychiatrist or other qualified health professional before making any changes to your medications or with any questions you may have regarding drugs/medications. In considering coming off psychiatric drugs it is very important that you are aware that most psychiatric drugs can cause withdrawal reactions, sometimes including life-threatening emotional and physical withdrawal problems. In short, it is not only dangerous to start taking psychiatric drugs, it can also be dangerous to stop them. Withdrawal from psychiatric drugs should only be done carefully under experienced clinical supervision.

CYP Testing to Help Prevent Dangerous Adverse Drug Reactions

cpuusage

cpuusage

ACCOUNT CLOSED
Joined
Sep 25, 2012
Messages
37,648
Location
Planet Lunatic Asylum
CYP Testing to Help Prevent Dangerous Adverse Drug Reactions - Mad In America

By
Selma Eikelenboom-Schieveld, MD
January 24, 2017

"Readers of this website might be aware that antidepressants can cause suicide, other violent behavior and even homicide. These can be side effects or adverse drug reactions from the medication taken. Not only can antidepressants cause these side effects, but basically every psychoactive medication can put patients at risk. Few people may know that there are DNA tests that can identify individuals who might be prone to these adverse drug reactions.1"

Rest in Link.
 
Last edited by a moderator:
F

firemonkee57

Well-known member
Joined
Mar 23, 2009
Messages
8,218
Via Promethease using my 23andMe data

CYP2C19
rs1045642(C;T)
Magnitude: 2
Frequency: 55.8%
Repute:Bad
References:106
Slower metaboliser for some drugs



CYP2D6
gs173
Magnitude: 2
CYP2D6*10
CYP2D6*10 reduced metabolism



rs1065852(C;T)
Magnitude: 2
Repute:Bad
References:8
Carrier of one CYP2D6 decreased or non-functioning variant. Your body may have a reduced ability to process some medicines. You are a carrier for rs1065852(T;T)



rs1135840(C;C)
Magnitude: 2
References:5
ambig
Homozygous for CYP2D6 variants (non-CYP2D6*1)


CYP3A5
gs155
Magnitude: 2.5
Repute: Bad
CYP3A5 non-expressor
This is common for Caucasians, but rare for African populations. As a CYP3A5 non-expressor you are unable to metabolize some common medications. This influences the synthesis of cholesterol, steroids and other lipids. The enzyme metabolizes drugs such as olanzapine, tacrolimus, nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.
 
Top