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Brain Changes in Schizophrenia Respond to Non-Drug Therapy

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firemonkee57

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Mar 23, 2009
Messages
8,225
A non-drug "cognitive enhancement therapy" stopped and even reversed the brain shrinkage that often accompanies schizophrenia, results of a randomized trial showed.

Patients with recent-onset schizophrenia who participated in two years of social-cognitive training and exercise sessions showed smaller losses in gray matter in some brain regions and greater increases in others, compared with a control group treated with conventional supportive therapy, reported Matcheri S. Keshavan, MD, of Beth Israel Deaconess Medical Center in Boston, and colleagues.

Cognitive enhancement therapy "can protect against gray matter loss and may even support gray matter growth in medial temporal areas of the brain in service of cognitive enhancement among patients with early course schizophrenia," Keshavan and colleagues wrote online in Archives of General Psychiatry.

The intervention included personalized computer-based neurocognitive training using such tools as the Orientation Remediation Module created by Yehuda Ben-Yishay, PhD, and PSSCogReHab software developed by Odie Bracy, PhD.

These sessions were conducted with pairs of patients, who also stayed together in group socialization and experiential learning sessions. Three or four patient pairs participated in these sessions, which included "both innovative cognitive exercises and psychoeducation that foster the development of social-cognitive abilities and effective social interaction," Keshavan and colleagues explained.

http://www.medpagetoday.com/Psychiatry/Schizophrenia/19886
 
W

wff

Guest
As an added perspective I quote from the fact-sheet entitled "Schizophrenia":

"Brain scans show that there are differences in the brains of some people with schizophrenia - but not in others."

Dr Philip Timms: Series Editor. "Schizophrenia". April 2010. The Royal College of Psychiatrists' Public Education Editorial Sub-Committee. Accessed: 2010-05-04.

The leaflet may be viewed via this link:

http://www.rcpsych.ac.uk/mentalhealthinfoforall/problems/schizophrenia/schizophrenia.aspx
 
Star-28

Star-28

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I had an MRI and an EEG done, and both were normal. Another reason my doc did not diagnose me with schizophrenia. I just do not know how she can say that when my tests were done years before I ever became psychotic. Maybe she thought I was just trying to seek attention since people with Borderline Personality Disorder have a rep for that. Totally not true.. for me anyway.

I have always wondered if my suicide attempt had anything to do with my symptoms becoming worse. I was without oxygen for a short time, and afterwards I had the worst headache of my life. Well since I have a new full time job now I will be getting some good insurance soon, and we'll just see what my doc says tomorrow.
 
I

IntrospectionFtw!

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Dec 3, 2009
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Buried under a sand castle.
I had an MRI and an EEG done, and both were normal. Another reason my doc did not diagnose me with schizophrenia. I just do not know how she can say that when my tests were done years before I ever became psychotic. Maybe she thought I was just trying to seek attention since people with Borderline Personality Disorder have a rep for that. Totally not true.. for me anyway.

I have always wondered if my suicide attempt had anything to do with my symptoms becoming worse. I was without oxygen for a short time, and afterwards I had the worst headache of my life. Well since I have a new full time job now I will be getting some good insurance soon, and we'll just see what my doc says tomorrow.
Yeah i had a brain scan when i was first put on these drugs they said i was perfectly normal. i've had two major episodes since then and they're refusing to even give me one now. even though i feel like im deteriating and need one.
 
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