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Augmentation of Schizophrenia Treatment

Lake

Lake

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Jan 29, 2020
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Chicago
Hi I'm Lake! I have been doing research into schizophrenia and found some interesting stuff on augmentation. Augmentation of treatment is adding an antidepressant to treatment to help combat negative symptoms and poor mood that can accompany schizophrenia! I have been talking with my psychiatrist and I think because I am depressed now would be a good time to try it. Has anyone tried augmentation before? How did it work for you?
 
EdEd

EdEd

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Dec 21, 2019
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I haven't tried it but the way you describe it makes it sound positively optimistic. Almost sounds like something that I want to try now. :)
 
L

linus

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Mar 27, 2019
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This is usually something to avoid, especially using ssri since it would also affect the serotonin uptake system just like the antipsychotics do, but it is sometimes prescribed.
However pretty often a pmed would prescribe a mood stabliser together with an sga (like depakine/depakote)
 
Lake

Lake

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This is usually something to avoid, especially using ssri since it would also affect the serotonin uptake system just like the antipsychotics do, but it is sometimes prescribed.
However pretty often a pmed would prescribe a mood stabliser together with an sga (like depakine/depakote)
I didn't know this, I will bring this up with my psychiatrist. He said he would tell me more next session.
 
vanish

vanish

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Let us know how you go @Lake because I'm interested in knowing more. I have been prescribed an antidepressant as well as antipsychotics, but this is because I have depression in kind. I do know of someone who has been prescribed a mild dose of an antidepressant (lexapro) in conjunction with antipsychotics (namely clozapine) to help combat negative symptoms though. They don't actually live with depression at all (or staunchly denies it).
 
C

Cocoa

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Feb 21, 2018
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I've been on an antidepressant for years - venlafaxine should I not take it along with my antipsychotics - clozapine and haloperidol?
 
daffy

daffy

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I was on quetiapine (antipsychotic) along with mirtazipine and duloxitine for years. I’m no longer on quetiapine. But taking that lot did make me very emotionless
 
JustMe1982

JustMe1982

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I have tried it but a lot of antidepressants mess with my stomach really bad. Especially zoloft. I have to start off with the lowest possible dose and work my way up.
 
L

linus

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I've been on an antidepressant for years - venlafaxine should I not take it along with my antipsychotics - clozapine and haloperidol?
You should talk to your medic about such advice. In all the protocols it is stated that this should be avoided, however it is the medic’s call because there are cases when it could be needed (especially on the affectice schizo type)
 
C

Cocoa

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Feb 21, 2018
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Thanks for the info I will bring it up with the Doctor when I see them in May I don't think the antidepressant works anyway
 
S

saynow

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Jul 8, 2016
Messages
178
Hi I'm Lake! I have been doing research into schizophrenia and found some interesting stuff on augmentation. Augmentation of treatment is adding an antidepressant to treatment to help combat negative symptoms and poor mood that can accompany schizophrenia! I have been talking with my psychiatrist and I think because I am depressed now would be a good time to try it. Has anyone tried augmentation before? How did it work for you?
Hi,lake
Any antidepressant added to my meds
I got depression from it
I tried it many times
Thanks god I havnt depression originally
 
L

Lab rat

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Feb 6, 2020
Messages
58
Location
UK
I won’t give you a list of what I’ve been on and the odd reactions I’ve had to them, my guess is that most of you probably have similar stories anyway

I’m currently on:

omeprazole (cos the meds have wrecked my stomach linings)
Duleoxetine 40mg I think?
Olanzapine 20mg top dose
Chlorpromazine 1000mg i think, not the ceiling dose
Zopiclone 15mg which replaced zolpidem 10mg because the chemist was unable to get the medication any more.

oh, and
Codeine 240mg split over the day
Bupronorpherine 2mg

the last 2 are for the fibromyalgia

I’ve been on this combination for years (except the change in sleeping pills which was about a year ago)

side effects: nothing really to write home about. Makes the negs worse and ties my brain up in knots (thought disorder).

I’m pretty compliant with my treatment but do have a habit of keep coming off the chlorpromazine. I find it makes the thought disorder much worse and causes me to slur. Sometimes I have to give presentations, and find myself slurring in front of a room full of people! Embarrassing! I just laugh it off, and tell them I had a stroke. Tbh it’s not too far from the truth, I took an od and had a stroke and died. The od is right around the time I started slurring. I have to stop , take a breath, think about what I want to say, and start again. Fortunately I only do a couple of presentations a month now, which is a lot better for me.
 
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