Another couple of things that come into play I think are low self esteem and feelings of guilt. Those, on their own aren't considered as a disorder like depression or anxiety can be. Maybe more symptomatic. But when I experience either anxiety or depression, I'm liable to feel my esteem slide down and start saying to myself 'how stupid can I be', 'I ruined everyone's day', 'nobody likes me', 'it's all my fault', 'why do I do such stupid things', 'I wish everyone would just leave me alone'. That all spills over into my actions too, like not going to a party because I'm 'no good' and 'people don't like me'. Like the way depression feeds on anxiety, it also feeds on the guilt feelings and low esteem, which in turn feed on the depression and/or anxiety. I find that now when I start to get into that downward spiral I vehemently tell myself '#*&ck it, this is how I'm going to be - I don't care what anyone else thinks' and then try to really push that. It doesn't always work but has been quite liberating the times when it has.