Depression: A revolution in treatment? - BBC News
He's at the forefront of this new approach: "Recent history is telling us if we want to make therapeutic breakthroughs in an area which remains incredibly important in terms of disability and suffering then we've got to think differently."
The focus is on an
errant immune system causing inflammation in the body and altering mood.
And Prof Bullmore argues that's something we can all relate to, if we just think back to the last time we had a cold or flu.
He said: "Depression and inflammation often go hand in hand, if you have flu, the immune system reacts to that, you become inflamed and very often people find that their mood changes too.
"Their behaviour changes, they may become less sociable, more sleepy, more withdrawn.
"They may begin to have some of the negative ways of thinking that are characteristic of depression and all of that follows an infection."